Gary Maartens Selected Research

Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis)

12/2022	Pharmacogenetics of Between-Individual Variability in Plasma Clearance of Bedaquiline and Clofazimine in South Africa.
10/2022	Assessing Prolongation of the Corrected QT Interval with Bedaquiline and Delamanid Coadministration to Predict the Cardiac Safety of Simplified Dosing Regimens.
1/2022	Optimized Loading Dose Strategies for Bedaquiline When Restarting Interrupted Drug-Resistant Tuberculosis Treatment.
1/2022	Linezolid toxicity in patients with drug-resistant tuberculosis: a prospective cohort study.
1/2022	An All-Oral 6-Month Regimen for Multidrug-Resistant Tuberculosis: A Multicenter, Randomized Controlled Clinical Trial (the NExT Study).
1/2022	Population Pharmacokinetics of Delamanid and its Main Metabolite DM-6705 in Drug-Resistant Tuberculosis Patients Receiving Delamanid Alone or Coadministered with Bedaquiline.
1/2022	Treatment outcomes 24 months after initiating short, all-oral bedaquiline-containing or injectable-containing rifampicin-resistant tuberculosis treatment regimens in South Africa: a retrospective cohort study.
1/2022	A treatment recommender clinical decision support system for personalized medicine: method development and proof-of-concept for drug resistant tuberculosis.
1/2022	Assessment of epidemiological and genetic characteristics and clinical outcomes of resistance to bedaquiline in patients treated for rifampicin-resistant tuberculosis: a cross-sectional and longitudinal study.
12/2021	Effectiveness and Cardiac Safety of Bedaquiline-Based Therapy for Drug-Resistant Tuberculosis: A Prospective Cohort Study.

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Gary Maartens Research Topics

Disease

88	Tuberculosis (Tuberculoses) 01/2022 - 05/2002
26	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 12/2022 - 05/2002
17	Immune Reconstitution Inflammatory Syndrome 01/2022 - 08/2007
12	Infections 01/2022 - 03/2009
8	Acquired Immunodeficiency Syndrome (AIDS) 11/2018 - 01/2006
7	HIV Infections (HIV Infection) 11/2021 - 05/2002
6	Weight Gain 03/2022 - 11/2018
6	Opportunistic Infections (Opportunistic Infection) 01/2022 - 08/2006
6	Drug-Related Side Effects and Adverse Reactions 01/2022 - 12/2009
5	Pulmonary Tuberculosis 01/2022 - 06/2007
4	Coinfection 01/2022 - 01/2017
4	Lipodystrophy 10/2018 - 01/2007
3	Meningeal Tuberculosis (Tuberculous Meningitis) 01/2022 - 01/2021
3	Cough 01/2022 - 01/2018
3	Sepsis (Septicemia) 01/2022 - 01/2017
3	Body Weight (Weight, Body) 01/2021 - 04/2017
3	Neurocognitive Disorders (Clerambault Syndrome) 01/2019 - 06/2015
3	Dyslipidemias (Dyslipidemia) 01/2016 - 08/2011
3	Latent Tuberculosis 12/2007 - 03/2007
2	Lymphadenopathy 01/2022 - 01/2022
2	Hearing Loss (Hearing Impairment) 01/2022 - 01/2020
2	Peripheral Nervous System Diseases (PNS Diseases) 04/2021 - 01/2007
2	Liver Diseases (Liver Disease) 10/2020 - 03/2012
2	Exanthema (Rash) 10/2020 - 11/2007
2	Bacterial Pneumonia 02/2020 - 01/2018
2	Hepatitis 01/2020 - 11/2007
2	Extensively Drug-Resistant Tuberculosis 12/2018 - 01/2018
2	Neoplasms (Cancer) 11/2018 - 08/2016
2	Pneumocystis Pneumonia (Pneumocystis carinii Pneumonia) 01/2018 - 01/2018
2	Respiratory Tract Infections (Respiratory Tract Infection) 01/2018 - 04/2015
2	Inflammation (Inflammations) 01/2017 - 08/2016
2	Hypersensitivity (Allergy) 11/2016 - 11/2007
2	Glucose Intolerance 09/2016 - 07/2010
1	COVID-19 06/2022
1	Malaria 01/2022
1	Anemia 01/2022
1	Critical Illness (Critically Ill) 01/2022
1	Psychotic Disorders (Schizoaffective Disorder) 04/2021
1	Cardiac Arrhythmias (Arrythmia) 01/2021

Drug/Important Bio-Agent (IBA)

30	Rifampin (Rifampicin)FDA LinkGeneric 01/2022 - 02/2008
24	Pharmaceutical PreparationsIBA 01/2022 - 08/2008
17	bedaquiline (R207910)IBA 12/2022 - 02/2017
16	efavirenz (Sustiva)FDA Link 03/2022 - 11/2007
12	dolutegravirIBA 03/2022 - 07/2017
11	Isoniazid (Ftivazide)FDA LinkGeneric 01/2022 - 01/2011
10	Linezolid (Zyvox)FDA Link 01/2022 - 11/2015
8	C-Reactive ProteinIBA 01/2022 - 01/2011
8	Lopinavir FDA Link 02/2017 - 04/2008
7	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2012
7	Ritonavir (Norvir)FDA Link 01/2020 - 04/2008
7	Nevirapine (Viramune)FDA Link 02/2017 - 11/2007
6	Prednisone (Sone)FDA LinkGeneric 01/2021 - 09/2010
5	lipoarabinomannan (LAM)IBA 01/2022 - 01/2019
5	Tenofovir (Viread)FDA Link 01/2021 - 11/2016
4	Clofazimine (Lamprene)FDA Link 12/2022 - 12/2018
4	OPC-67683IBA 10/2022 - 01/2021
4	FluoroquinolonesIBA 01/2022 - 05/2002
4	tenofovir alafenamideIBA 01/2021 - 07/2017
4	Emtricitabine (Emtriva)FDA Link 01/2021 - 01/2019
4	Proteins (Proteins, Gene)FDA Link 11/2018 - 06/2007
3	terizidoneIBA 01/2022 - 10/2020
3	Hemoglobins (Hemoglobin)IBA 01/2022 - 01/2018
3	Cycloserine (Seromycin)FDA Link 01/2022 - 10/2020
3	AcidsIBA 01/2022 - 01/2011
3	Tuberculin (PPD)IBA 01/2021 - 06/2007
3	Antitubercular AgentsIBA 01/2021 - 03/2009
3	Anti-Bacterial Agents (Antibiotics)IBA 02/2020 - 04/2015
3	GlucocorticoidsIBA 11/2018 - 10/2007
3	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2016 - 06/2009
3	AntigensIBA 08/2012 - 06/2007
3	Reverse Transcriptase InhibitorsIBA 08/2011 - 11/2007
2	Cytochrome P-450 CYP2B6 (CYP2B6)IBA 03/2022 - 12/2021
2	Kanamycin FDA Link 01/2022 - 01/2020
2	RNA (Ribonucleic Acid)IBA 12/2021 - 10/2020
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2020 - 01/2019
2	ProcalcitoninIBA 01/2018 - 01/2017
2	CytokinesIBA 01/2017 - 04/2013
2	Glucose (Dextrose)FDA LinkGeneric 09/2016 - 07/2010
2	Stavudine (Zerit)FDA LinkGeneric 07/2010 - 01/2007
2	EnzymesIBA 11/2008 - 06/2007
2	NucleosidesIBA 05/2008 - 11/2007
1	SuspensionsIBA 06/2022
1	NitroimidazolesIBA 01/2022
1	Integrase InhibitorsIBA 01/2022
1	piperaquineIBA 01/2022
1	Dihydrotachysterol (AT 10)IBA 01/2022
1	AlbuminsIBA 01/2022
1	Aminosalicylic Acid (Rezipas)FDA Link 01/2022
1	Carbapenems (Carbapenem Antibiotics)IBA 01/2022
1	artenimol (dihydroartemisinin)IBA 01/2022
1	Pyridoxine (Pyridoxin)FDA LinkGeneric 04/2021

Therapy/Procedure

45	Therapeutics 01/2022 - 05/2002
22	Art Therapy 01/2022 - 01/2006
9	Highly Active Antiretroviral Therapy (HAART) 06/2015 - 05/2002
4	Injections 01/2022 - 01/2018
2	Aftercare (After-Treatment) 01/2022 - 10/2020
2	Duration of Therapy 01/2022 - 10/2019
2	Drug Therapy (Chemotherapy) 03/2017 - 06/2008
1	Drug Substitution 01/2022
1	Precision Medicine 01/2022